Optoelectrodes: Silicon Probes for Optogenetics

NeuroNexus optoelectrodes integrate optical fibers with silicon-based neural probes, enabling simultaneous optogenetic stimulation and high-resolution electrophysiological recording. This combination allows researchers to precisely control neuronal activity while monitoring neural responses in real-time.

Key Features:

• Integrated Design: Optical fibers are laminated onto silicon probes, facilitating concurrent optical stimulation and electrical recording.
• Customization: Researchers can select from various electrode array designs and fiber types, specifying termination locations with 50 µm accuracy to target specific brain regions or neuronal populations.
• Minimal Photoelectric Artifacts: Engineered to reduce photoelectric artifacts, ensuring accurate data collection during experiments

Specifications:

• Fiber Dimensions and Numerical Aperture (NA):
  • 50 µm core / 62.5 µm outer diameter (OD) – 0.22 NA​
  • 105 µm core / 125 µm OD – 0.22 NA​
  • 200 µm core / 220 µm OD – 0.22 NA​
  • 200 µm core / 225 µm OD – 0.39 NA​
  • 400 µm core / 425 µm OD – 0.39 NA​
  • 50 µm core / 62.5 µm OD – 0.66 NA​
  • 105 µm core / 125 µm OD – 0.66 NA​
  • 200 µm core / 220 µm OD – 0.66 NA​
• Coupler Weight: Less than 0.5 grams.​
• Durability: Maintains less than 5% transmission variability after 40 connections.​
• Rotation Stability: Exhibits less than 2% variation over one full rotation.​
• Connection Strength: Withstands over 300 grams of shear force before latch separation; maximum shear force exceeds 900 grams when applied to the top of the female coupler.​
• Length Tolerance: ±500 µm.​

Fiber Placement Options:

• Single-Fiber Configuration: An optical fiber (flat or tapered) is positioned on the recording side of the shank, terminating at the desired location above the proximal recording site with 50 µm precision.​
• Multi-Fiber Configuration: Multi-shank microelectrode arrays can be equipped with one fiber per shank, either directly over the shank or positioned between them, allowing for complex stimulation patterns and targeting multiple brain areas.​

Tapered-tip Fiber Placement and Illumination Options

Available Models:

Ordering Information:

NeuroNexus optoelectrodes can be customized to meet specific experimental requirements. Researchers can choose from various electrode configurations, fiber types, and placement options to design an optoelectrode tailored to their studies